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Showing 1 to 12 of 107 entries
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Solid lipid nanoparticle: an efficient carrier for improved ocular permeation of voriconazole.

Drug development and industrial pharmacy

Kumar R, Sinha VR.
PMID: 27143048
Drug Dev Ind Pharm. 2016 Dec;42(12):1956-1967. doi: 10.1080/03639045.2016.1185437. Epub 2016 May 20.

This research focuses on the fabrication and evaluation of solid lipid nanoparticles (SLNs) for improved ocular delivery of voriconazole (VCZ). Compritol and palmitic acid were selected as lipid carriers based on drug solubility and partitioning behavior. Poloxamer and soya...

Two steps modification for improvement of cyclobenzaprine transdermal delivery: releasing from patch and penetrating through skin.

Drug development and industrial pharmacy

Lv S, Quan P, Wang W, Fang L.
PMID: 27436573
Drug Dev Ind Pharm. 2016 Dec;42(12):2070-2077. doi: 10.1080/03639045.2016.1195402. Epub 2016 Jul 19.

The aim of this study was to improve the transdermal delivery of cyclobenzaprine (CBZ) from drug-in-adhesive patch which showed less side effects and better compliance. CBZ base was prepared and then characterized using differential scanning calorimetry (DSC). The interaction...

Doxorubicin- and cisplatin-loaded nanostructured lipid carriers for breast cancer combination chemotherapy.

Drug development and industrial pharmacy

Di H, Wu H, Gao Y, Li W, Zou D, Dong C.
PMID: 27184819
Drug Dev Ind Pharm. 2016 Dec;42(12):2038-2043. doi: 10.1080/03639045.2016.1190743. Epub 2016 Jun 01.

CONTEXT: Combination anticancer therapy is promising to generate synergistic anticancer effects, to maximize the treatment effect and to overcome multi-drug resistance. Nanostructured lipid carriers (NLCs), composed of solid and liquid lipids, and surfactants are potentially good colloidal drug carriers.OBJECTIVE:...

Hydrogel containing adapalene- and dapsone-loaded lipid-core nanocapsules for cutaneous application: development, characterization, in vitro irritation and permeation studies.

Drug development and industrial pharmacy

Pereira RL, Leites FI, Paese K, Sponchiado RM, Michalowski CB, Guterres SS, Schapoval EE.
PMID: 27161601
Drug Dev Ind Pharm. 2016 Dec;42(12):2001-2008. doi: 10.1080/03639045.2016.1188110. Epub 2016 May 31.

Lipid-core polymeric nanocapsule suspensions containing adapalene and dapsone (AD-LCNC) were developed and incorporated in a Carbopol 940® hydrogel (AD-LCNC HG). A nanoemulsion (AD-NE), similarly prepared but omitting the polymer, was developed and also incorporated in a Carbopol 940

Evaluation of the methylene blue addition in binary polymeric systems composed by poloxamer 407 and Carbopol 934P using quality by design: rheological, textural, and mucoadhesive analysis.

Drug development and industrial pharmacy

Junqueira MV, Borghi-Pangoni FB, Ferreira SB, Bruschi ML.
PMID: 27161762
Drug Dev Ind Pharm. 2016 Dec;42(12):2009-2019. doi: 10.1080/03639045.2016.1188111. Epub 2016 Jun 01.

This study describes the investigation about the physicochemical behavior of methylene blue (Mb) addition to systems containing poloxamer 407 (Polox), Carbopol 934P (Carb), intended to be locally used by photodynamic therapy. A factorial design 2

Simvastatin-loaded lyophilized wafers as a potential dressing for chronic wounds.

Drug development and industrial pharmacy

Rezvanian M, Tan CK, Ng SF.
PMID: 27237190
Drug Dev Ind Pharm. 2016 Dec;42(12):2055-2062. doi: 10.1080/03639045.2016.1195400. Epub 2016 Jun 24.

Wafers are an established drug delivery system for application to suppurating wounds. They can absorb wound exudates and are converted into a gel, offering a moist environment that is vital for wound healing. Simvastatin-loaded lyophilized wafers were developed using...

Natural polysaccharides platforms for oral controlled release of ketoprofen lysine salt.

Drug development and industrial pharmacy

Cerciello A, Auriemma G, Del Gaudio P, Cantarini M, Aquino RP.
PMID: 27237337
Drug Dev Ind Pharm. 2016 Dec;42(12):2063-2069. doi: 10.1080/03639045.2016.1195401. Epub 2016 Jun 14.

CONTEXT: Ketoprofen lysinate (KL) is one of the most widely used non-steroidal anti-inflammatory drugs in the symptomatic treatment of some chronic inflammatory diseases. Compared to ketoprofen, KL shows better pharmacokinetics and tolerability. However, due to its short half-life of...

Advances in dissolution instrumentation and their practical applications.

Drug development and industrial pharmacy

Culen M, Dohnal J.
PMID: 24093430
Drug Dev Ind Pharm. 2014 Oct;40(10):1277-82. doi: 10.3109/03639045.2013.841184. Epub 2013 Oct 04.

The rising demands on discriminatory and prediction abilities of dissolution methods and the increasing complexity of new drug products are the main driving forces of the progress in this field. The research moves forward as imperfections and shortcomings of...

Correction.

Drug development and industrial pharmacy

[No authors listed]
PMID: 32031017
Drug Dev Ind Pharm. 2020 Feb;46(2):I. doi: 10.1080/03639045.2020.1726015. Epub 2020 Feb 07.

No abstract available.

Correction to: Hanafy et al., Dual effect biodegradable ciprofloxacin loaded implantable matrices for osteomyelitis: controlled release and osteointegration.

Drug development and industrial pharmacy

[No authors listed]
PMID: 29877742
Drug Dev Ind Pharm. 2018 Sep;44(9):1564. doi: 10.1080/03639045.2018.1467824. Epub 2018 Jun 07.

No abstract available.

Correction to: Jake et al., Formulation and delivery strategies of ibuprofen: challenges and opportunities.

Drug development and industrial pharmacy

[No authors listed]
PMID: 29882683
Drug Dev Ind Pharm. 2018 Sep;44(9):1563. doi: 10.1080/03639045.2018.1467348. Epub 2018 Jun 08.

No abstract available.

Palatability of pediatric formulations: do rats predict aversiveness?.

Drug development and industrial pharmacy

Simões S, Almeida AJ, Marto J.
PMID: 34545750
Drug Dev Ind Pharm. 2021 Jul;47(7):1121-1126. doi: 10.1080/03639045.2021.1984519. Epub 2021 Sep 29.

BACKGROUND: The brief-access taste aversion (BATA) model has been used as an alternative taste assessment tool to human taste panels and became an important element of pharmaceutical drug development, especially regarding pediatric patient's compliance. This model has been validated,...

Showing 1 to 12 of 107 entries